A Review on Pharmacosomes as Novel Drug Delivery Systems

Abstract

Pharmacosomes are drug-lipid complexes that can form ultrafine vesicular, micellar, or hexagonal aggregates based on their chemical structure. It is based on the concept that a drug binds covalently to a lipid, with the resulting molecule being the carrier and the active chemical are present at the same time. The physicochemical qualities vary depending on both the medication and the lipid. Pharmacosomes: As offer advantages over conventional vesicles, making them a promising alternative. Encapsulating drugs in small amphiphilic vesicles prolongs their circulation, decreases toxicity, and increases efficacy. Cell wall transfer and the solubility of a poorly water-soluble chemical. This review covers Pharmacosomes' composition, synthesis, characterization, and therapeutic applications. Drug pharmacosomes are an effective method of delivering the medication directly to the infection site, which contributes a decrease in drug toxicity without harmful effects. They also reduce the cost of therapy by increasing the drug's bioavailability, especially for poorly soluble drugs. Pharmacosomes are suitable for incorporating both hydrophilic and lipophilic medication. Pharmacosomes have been developed for a variety of anti-inflammatory drugs, including nonsteroidal, neurological drugs.