Insight of Tuberculosis: Complications and Adverse Drug of Anti-Tubercular Medication

Abstract

Tuberculosis (TB) remains a leading infectious killer globally. TB is c Tuberculosis (TB) is a persistent global health challenge with significant complications. Apart from its direct effects on the lungs and other organs, TB can also lead to complications such as meningitis, bone and joint infections, and even pericardial involvement. These complications can be severe and may require extensive treatment and management. Additionally, the long-term use of anti-TB drugs can introduce its own set of complications. Hepatotoxicity is a well-known concern with drugs like isoniazid, rifampicin, and pyrazinamide, potentially leading to liver inflammation and dysfunction. Arthralgia, flu-like symptoms, hyperuricemia, thrombocytopenia, and peripheral neuropathy are also possible complications associated with prolonged use of these medications. Managing these complications requires close monitoring by healthcare providers and pharmacists, along with patient education on recognizing and reporting adverse effects promptly to ensure effective TB treatment while minimizing drug-related complications.