Cerebral Cortical Dysregulation in Attention-Deficit/Hyperactivity Disorder: Investigating Prefrontal Cortex Dysfunction, Dopaminergic Dysregulation, and Neurogenetic Correlates for Therapeutic Insights

Abstract

neurodevelopmental condition characterized by inattention, hyperactivity, and impulsivity, significantly impacting various aspects of an individual's life. This study focuses on investigating the cerebral cortical dysregulation evident in ADHD, specifically emphasizing prefrontal cortex dysfunction, dopaminergic irregularities, and neurogenetic correlates. The paper aims to unveil the intricate interplay between these factors and their collective contribution to the manifestation of ADHD symptoms. Through an extensive review of literature and empirical investigation, this study seeks to elucidate the underlying mechanisms of ADHD, providing a deeper understanding of the disorder's neurobiological underpinnings. Moreover, the exploration of these complex interactions is intended to offer insights into more precise and effective therapeutic interventions for individuals affected by ADHD, potentially paving the way for targeted treatments and management strategies tailored to the unique neurobiological profiles of those with ADHD.