Microwave Mediated Synthesis of Novel 1,3,5-Triazine Derivative and their Biological Evaluation

Authors

  • Krishn Kumar Barmase Department of Pharmaceutical Chemistry, Technocrats Institute of Technology-Pharmacy, Bhopal, India
  • Deepak Basedia Department of Pharmaceutical Chemistry, Technocrats Institute of Technology-Pharmacy, Bhopal, India
  • Balkrishna Dubey Department of Pharmaceutical Chemistry, Technocrats Institute of Technology-Pharmacy, Bhopal, India

DOI:

https://doi.org/10.47607/ijresm.2020.433

Keywords:

Antibacterial activity, Microwave irradiation, 1,3,5-Triazine

Abstract

1,3,5-Triazine derivative are synthesized by replacement of chloride ions of Cyanuric chloride and 1,3,5-Triazine derivative are showing promising biologically activity such as Antibacterial, Antifungal, Antimalarial, Antivirus, Anticancer that’s why interest of researches on synthesis of 1,3,5-Triazine derivatives always in focused. The present study reported the synthesis of 2,4,6-Trisubstituted 1,3,5-Triazine derivatives by Microwave mediated Method which gave the desired result in less time with higher yield. The structure of 1,3,5-Triazine derivatives have been elucidated by Spectral of IR, NMR and MASS. The derivative of 1,3,5-Triazine are evaluated for their In vitro Antibacterial activity against Gram Positive and Gram Negative Bacterial species and shown good Antibacterial effect.

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Published

03-01-2021

How to Cite

[1]
K. K. Barmase, D. Basedia, and B. Dubey, “Microwave Mediated Synthesis of Novel 1,3,5-Triazine Derivative and their Biological Evaluation”, IJRESM, vol. 3, no. 12, pp. 181–185, Jan. 2021.

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Articles